peptides.api

Sermorelin

approved

Also known as: GHRH (1-29), GRF 1-29

GHRH(1-29) analog that binds pituitary GHRH receptors to stimulate pulsatile growth hormone release.

Key data

Category
Growth Hormone Peptides
Molecular weight
3357.9 g/mol
Molecular formula
C149H246N44O42S
CAS number
86168-78-7
Half-life
10-20 minutes
Administration
subcutaneous
Research status
approved
References
22
Tags
ghrh-analog, gh-secretagogue

Research & studies

A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review
The Journal of sports medicine and physical fitness · 2026 · PubMed
Chromatographic-mass spectrometric analysis of peptidic analytes (2-10 kDa) in doping control urine samples
Journal of mass spectrometry : JMS · 2024 · PubMed
Cationic exchange SPE combined with triple quadrupole UHPLC-MS/MS for detection of GHRHs in urine samples
Analytical biochemistry · 2023 · PubMed
In-house standards derived from doping peptides: Enzymatic and serum stability and degradation profile of GHRP and GHRH-related peptides
Biomedical chromatography : BMC · 2023 · PubMed
Online large volume sample staking preconcentration and separation of enantiomeric GHRH analogs by capillary electrophoresis
Electrophoresis · 2023 · PubMed
An antibody-free, ultrafiltration-based assay for the detection of growth hormone-releasing hormones in urine at low pg/mL concentrations using nanoLC-HRMS/MS
Journal of pharmaceutical and biomedical analysis · 2022 · PubMed
A potentially effective drug for patients with recurrent glioma: sermorelin
Annals of translational medicine · 2021 · PubMed
Qualitative identification of growth hormone-releasing hormones in human plasma by means of immunoaffinity purification and LC-HRMS/MS
Analytical and bioanalytical chemistry · 2016 · PubMed

Frequently asked questions

What is Sermorelin?

GHRH(1-29) analog that binds pituitary GHRH receptors to stimulate pulsatile growth hormone release.

How does Sermorelin work?

GHRH(1-29) analog that binds pituitary GHRH receptors to stimulate pulsatile growth hormone release.

What is the research status of Sermorelin?

Sermorelin is currently classified as approved, with 22 research references on record. This is for research purposes only and is not medical advice.

What is the half-life of Sermorelin?

The reported half-life of Sermorelin is 10-20 minutes.

What is the molecular weight of Sermorelin?

Sermorelin has a molecular weight of approximately 3357.9 g/mol (formula C149H246N44O42S).

Related peptides

Somatostatin

Endogenous cyclic peptide that inhibits GH, insulin, glucagon, and gastric secretion via SSTR1-5 receptors.

Ghrelin

Endogenous 28-aa 'hunger hormone' from the stomach; activates GHS-R1a to stimulate GH release and appetite.

GHRP-6

First-generation ghrelin receptor agonist hexapeptide that stimulates GH release and strongly increases appetite.

Hexarelin

Potent GHRP-family ghrelin receptor agonist with studied cardioprotective effects independent of GH release.

GHRP-2

Synthetic hexapeptide ghrelin receptor agonist that potently stimulates GH secretion; also raises appetite, cortisol, and prolactin.

Tesamorelin

Stabilized GHRH analog approved for HIV-associated lipodystrophy; reduces visceral adipose tissue via GH/IGF-1 axis stimulation.

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